Assay Detail

CHEMBL1023019

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Functional

Cytotoxicity against mouse Ehrlich carcinoma cells

ChEMBL ↗

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Target

Ehrlich (CHEMBL614641) ↗

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Primary target Ehrlich

CHEMBL614641

Anchored from Assay target.

Protein identity Ehrlich

Disease frame Disease evidence pending

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Review focus Open DB context pending

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Total Activities

Compounds Tested

Activity Types

Assay Parameters

Assay Information

Assay Type	Functional
Organism	Mus musculus
Cell Type	Ehrlich
Confidence	1 — Organism
Curated By	Autocuration

Target

Ehrlich (CHEMBL614641) ↗

Type	CELL-LINE
Organism	Mus musculus

Publication

Discovery of novel Trypanosoma cruzi glyceraldehyde-3-phosphate dehydrogenase inhibitors.

Freitas RF, Prokopczyk IM, Zottis A, Oliva G, Andricopulo AD, Trevisan MT, Vilegas W, Silva MG, Montanari CA.
Bioorg Med Chem (2009) 17 : 2476 -2482
PubMed 19254846 · DOI

Activity Statistics

Type	Count	Avg pChEMBL	Best pChEMBL
IC50	1	4.16	4.16

Compounds Tested

Compound	Name	Phase	Activities	Best pChEMBL
CHEMBL266564	TILIROSIDE	—	1	4.16

Activity Data

Compound	Name	Type	Rel.	Value	Units	pChEMBL
CHEMBL266564	TILIROSIDE	IC50	=	69500.0	nM	4.16