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Assay Detail

CHEMBL1023574

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Functional
Antiplasmodial activity after 42 hrs against chloroquine-resistant Plasmodium falciparum K1 treated for 6 hrs by Giemsa stain
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Plasmodium falciparum
Confidence 1 — Organism
Curated By Autocuration

Target

Plasmodium falciparum (CHEMBL364)
Type ORGANISM
Organism Plasmodium falciparum

Publication

Interactions of methylene blue with human disulfide reductases and their orthologues from Plasmodium falciparum.
Buchholz K, Schirmer RH, Eubel JK, Akoachere MB, Dandekar T, Becker K, Gromer S.
Antimicrob Agents Chemother (2008) 52 : 183 -191
PubMed 17967916 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
EC50 1 8.19 8.19

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL405110 METHYLENE BLUE ANHYDROUS 4.0 1 8.19

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL405110 METHYLENE BLUE ANHYDROUS EC50 = 6.5 nM 8.19