Assay Detail
Functional
CHEMBL1023709
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Cytotoxicity against human HCT8 cells after 72 hrs by MTT assay
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | HCT-8 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
A diaryl sulfide, sulfoxide, and sulfone bearing structural similarities to combretastatin A-4.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 6.21 | 7.40 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL553871 | — | — | 1 | 7.40 |
| CHEMBL561955 | — | — | 1 | 6.33 |
| CHEMBL561956 | — | — | 1 | 4.91 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL553871 | — | IC50 | = | 40.0 | nM | 7.40 |
| CHEMBL561955 | — | IC50 | = | 470.0 | nM | 6.33 |
| CHEMBL561956 | — | IC50 | = | 12250.0 | nM | 4.91 |