Assay Detail
Binding
CHEMBL1024114
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Inhibition of tubulin polymerization
6
Total Activities
6
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
Current developments in the discovery and design of new drug candidates from plant natural product leads.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 6 | 6.17 | 6.25 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL368737 | THIOCOLCHICONE | — | 1 | 6.25 |
| CHEMBL49847 | — | — | 1 | 6.25 |
| CHEMBL368670 | — | — | 1 | 6.25 |
| CHEMBL176684 | — | — | 1 | 6.25 |
| CHEMBL107 | COLCHICINE | 4.0 | 1 | 6.19 |
| CHEMBL18981 | THIOCOLCHICINE | — | 1 | 5.82 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL368737 | THIOCOLCHICONE | IC50 | = | 560.0 | nM | 6.25 |
| CHEMBL49847 | — | IC50 | = | 560.0 | nM | 6.25 |
| CHEMBL368670 | — | IC50 | = | 560.0 | nM | 6.25 |
| CHEMBL176684 | — | IC50 | = | 560.0 | nM | 6.25 |
| CHEMBL107 | COLCHICINE | IC50 | = | 650.0 | nM | 6.19 |
| CHEMBL18981 | THIOCOLCHICINE | IC50 | = | 1500.0 | nM | 5.82 |