Assay Detail
Functional
CHEMBL1024349
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Antiviral activity against Epstein-Barr virus in human Akata cells by DNA hybridization assay
5
Total Activities
5
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Human gammaherpesvirus 4 |
| Cell Type | Akata |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Phosphonate analogues of cyclopropavir phosphates and their E-isomers. Synthesis and antiviral activity.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 5 | 6.09 | 6.66 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL265948 | FILOCICLOVIR | 2.0 | 1 | 6.66 |
| CHEMBL554910 | — | — | 1 | 5.51 |
| CHEMBL572812 | — | — | 1 | - |
| CHEMBL550615 | — | — | 1 | - |
| CHEMBL559499 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL265948 | FILOCICLOVIR | EC50 | = | 220.0 | nM | 6.66 |
| CHEMBL554910 | — | EC50 | = | 3100.0 | nM | 5.51 |
| CHEMBL572812 | — | EC50 | > | 100000.0 | nM | - |
| CHEMBL550615 | — | EC50 | > | 100000.0 | nM | - |
| CHEMBL559499 | — | EC50 | > | 100000.0 | nM | - |