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Assay Detail

CHEMBL1024361

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Antiviral activity against Herpes simplex virus type 1 in african green monkey BSC1 cells by ELISA
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Human alphaherpesvirus 1
Cell Type BSC-1
Confidence 1 — Organism
Curated By Autocuration

Target

Human alphaherpesvirus 1 (CHEMBL377)
Type ORGANISM
Organism Human alphaherpesvirus 1

Publication

Phosphonate analogues of cyclopropavir phosphates and their E-isomers. Synthesis and antiviral activity.
Mhaske SB, Ksebati B, Prichard MN, Drach JC, Zemlicka J.
Bioorg Med Chem (2009) 17 : 3892 -3899
PubMed 19410465 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
EC50 2 4.82 4.82

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL554910 1 4.82
CHEMBL265948 FILOCICLOVIR 2.0 1 -

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL554910 EC50 = 15000.0 nM 4.82
CHEMBL265948 FILOCICLOVIR EC50 > 100000.0 nM -