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Assay Detail

CHEMBL1024590

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Functional
Antiproliferative activity against human SF268 cells after three generation of incubation by MTS assay
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Homo sapiens
Cell Type SF-268
Confidence 1 — Organism
Curated By Autocuration

Target

SF-268 (CHEMBL613977)
Type CELL-LINE
Organism Homo sapiens

Publication

Generation of ligand-based pharmacophore model and virtual screening for identification of novel tubulin inhibitors with potent anticancer activity.
Chiang YK, Kuo CC, Wu YS, Chen CT, Coumar MS, Wu JS, Hsieh HP, Chang CY, Jseng HY, Wu MH, Leou JS, Song JS, Chang JY, Lyu PC, Chao YS, Wu SY.
J Med Chem (2009) 52 : 4221 -4233
PubMed 19507860 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 6.50 6.50

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL564979 1 6.50

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL564979 IC50 = 319.0 nM 6.50