Assay Detail
Binding
CHEMBL1024602
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of tubulin polymerization
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
Generation of ligand-based pharmacophore model and virtual screening for identification of novel tubulin inhibitors with potent anticancer activity.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 5.39 | 5.77 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL562718 | INDANOCINE | — | 1 | 5.77 |
| CHEMBL7976 | CHALCONE | — | 1 | 5.00 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL562718 | INDANOCINE | IC50 | = | 1700.0 | nM | 5.77 |
| CHEMBL7976 | CHALCONE | IC50 | = | 10000.0 | nM | 5.00 |