Assay Detail
Binding
CHEMBL1024696
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Displacement of [3H]DPDPE from human delta opioid receptor expressed in mouse HN9.10 cell membrane by liquid scintillation counting
7
Total Activities
4
Compounds Tested
2
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
The importance of micelle-bound states for the bioactivities of bifunctional peptide derivatives for delta/mu opioid receptor agonists and neurokinin 1 receptor antagonists.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 4 | 8.92 | 9.36 |
| IC50 | 3 | 8.70 | 9.10 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL448998 | — | — | 2 | 9.36 |
| CHEMBL507340 | — | — | 2 | 9.18 |
| CHEMBL200199 | BIPHALIN | — | 1 | 8.59 |
| CHEMBL389652 | — | — | 2 | 8.55 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL448998 | — | Ki | = | 0.44 | nM | 9.36 |
| CHEMBL507340 | — | Ki | = | 0.66 | nM | 9.18 |
| CHEMBL448998 | — | IC50 | = | 0.7943 | nM | 9.10 |
| CHEMBL507340 | — | IC50 | = | 1.585 | nM | 8.80 |
| CHEMBL200199 | BIPHALIN | Ki | = | 2.6 | nM | 8.59 |
| CHEMBL389652 | — | Ki | = | 2.8 | nM | 8.55 |
| CHEMBL389652 | — | IC50 | = | 6.31 | nM | 8.20 |