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Assay Detail

CHEMBL1024724

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Cytotoxicity against human CA46 cell after 48 hrs by MTT assay
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Homo sapiens
Cell Type CA46
Confidence 1 — Organism
Curated By Autocuration

Target

CA46 (CHEMBL612566)
Type CELL-LINE
Organism Homo sapiens

Publication

5-N-methylated quindoline derivatives as telomeric g-quadruplex stabilizing ligands: effects of 5-N positive charge on quadruplex binding affinity and cell proliferation.
Lu YJ, Ou TM, Tan JH, Hou JQ, Shao WY, Peng D, Sun N, Wang XD, Wu WB, Bu XZ, Huang ZS, Ma DL, Wong KY, Gu LQ.
J Med Chem (2008) 51 : 6381 -6392
PubMed 18821749 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 5.87 5.87

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL491432 1 5.87

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL491432 IC50 = 1360.0 nM 5.87