Assay Detail
Binding
CHEMBL1024774
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Binding affinity to human PNMT K57A mutant by liquid scintillation spectrometry in presence of [3H]AdoMet
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Target
Phenylethanolamine N-methyltransferase (CHEMBL4617) ↗| Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
Publication
Time-dependent inactivation of human phenylethanolamine N-methyltransferase by 7-isothiocyanatotetrahydroisoquinoline.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 2 | 5.37 | 5.58 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL459366 | — | — | 1 | 5.58 |
| CHEMBL26717 | — | — | 1 | 5.16 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL459366 | — | Ki | = | 2600.0 | nM | 5.58 |
| CHEMBL26717 | — | Ki | = | 6900.0 | nM | 5.16 |