Assay Detail
Binding
CHEMBL1024928
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of tubulin polymerization
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
Antitumor agents, 154. Cytotoxic and antimitotic flavonols from Polanisia dodecandra.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 4 | 5.88 | 6.08 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL18351 | — | — | 1 | 6.08 |
| CHEMBL107 | COLCHICINE | 4.0 | 1 | 5.85 |
| CHEMBL77552 | CENTAUREIDIN | — | 1 | 5.70 |
| CHEMBL61 | PODOFILOX | 4.0 | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL18351 | — | IC50 | = | 830.0 | nM | 6.08 |
| CHEMBL107 | COLCHICINE | IC50 | = | 1400.0 | nM | 5.85 |
| CHEMBL77552 | CENTAUREIDIN | IC50 | = | 2000.0 | nM | 5.70 |
| CHEMBL61 | PODOFILOX | IC50 | - | — | - |