Assay Detail
Functional
CHEMBL1025148
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Antitumor activity against mouse L1210 cells
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Mus musculus |
| Cell Type | L1210 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Recent advances in the development of polyamine analogues as antitumor agents.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 4 | 6.41 | 6.70 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL44083 | BIS(ETHYL)NORSPERMINE | — | 1 | 6.70 |
| CHEMBL18794 | BIS(ETHYL)SPERMINE | — | 1 | 6.30 |
| CHEMBL76840 | — | — | 1 | 6.22 |
| CHEMBL27909 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL44083 | BIS(ETHYL)NORSPERMINE | IC50 | = | 200.0 | nM | 6.70 |
| CHEMBL18794 | BIS(ETHYL)SPERMINE | IC50 | = | 500.0 | nM | 6.30 |
| CHEMBL76840 | — | IC50 | = | 600.0 | nM | 6.22 |
| CHEMBL27909 | — | IC50 | - | — | - |