Assay Detail

CHEMBL1025166

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional

Antitumor activity against human MDA-MB-468 cells

ChEMBL ↗

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Target

MDA-MB-468 (CHEMBL614335) ↗

Open DB target context

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MDA-MB-468 (CHEMBL614335) is the working anchor for this assay review. Loading the live Open DB target snapshot…

Primary target MDA-MB-468

CHEMBL614335

Anchored from Assay target.

Protein identity MDA-MB-468

Disease frame Disease evidence pending

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Review focus Open DB context pending

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Total Activities

Compounds Tested

Activity Types

Assay Parameters

Assay Information

Assay Type	Functional
Organism	Homo sapiens
Cell Type	MDA-MB-468
Confidence	1 — Organism
Curated By	Autocuration

Target

MDA-MB-468 (CHEMBL614335) ↗

Type	CELL-LINE
Organism	Homo sapiens

Publication

Recent advances in the development of polyamine analogues as antitumor agents.

Casero RA, Woster PM.
J Med Chem (2009) 52 : 4551 -4573
PubMed 19534534 · DOI

Activity Statistics

Type	Count	Avg pChEMBL	Best pChEMBL
IC50	1	6.70	6.70

Compounds Tested

Compound	Name	Phase	Activities	Best pChEMBL
CHEMBL33387	—	—	1	6.70

Activity Data

Compound	Name	Type	Rel.	Value	Units	pChEMBL
CHEMBL33387	—	IC50	=	200.0	nM	6.70