Assay Detail
Binding
CHEMBL1025544
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of His6x-tagged yeast recombinant Esa1 (105-445) expressed in Escherichia coli BL21 (DE3) using acetyl-CoA as substrate by competitive binding
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Saccharomyces cerevisiae |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
Bisubstrate Inhibitors of the MYST HATs Esa1 and Tip60.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 1 | 6.13 | 6.13 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL504265 | — | — | 1 | 6.13 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL504265 | — | Ki | = | 740.0 | nM | 6.13 |