Assay Detail
Functional
CHEMBL1026006
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Cytotoxicity against mouse B16F10 cells after 72 hrs by MTT assay
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Mus musculus |
| Cell Type | B16-F10 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Hydroxychalcones induce apoptosis in B16-F10 melanoma cells via GSH and ATP depletion.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 4.74 | 4.92 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL487233 | — | — | 1 | 4.92 |
| CHEMBL487051 | — | — | 1 | 4.77 |
| CHEMBL487126 | — | — | 1 | 4.52 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL487233 | — | IC50 | = | 12000.0 | nM | 4.92 |
| CHEMBL487051 | — | IC50 | = | 17000.0 | nM | 4.77 |
| CHEMBL487126 | — | IC50 | = | 30000.0 | nM | 4.52 |