Assay Detail
Functional
CHEMBL1026423
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Antagonist activity at human cloned 5HT2A receptor
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Synthesis, binding affinity, and molecular docking analysis of new benzofuranone derivatives as potential antipsychotics.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 4 | 8.02 | 9.25 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL164471 | — | — | 1 | 9.25 |
| CHEMBL143027 | — | — | 1 | 7.95 |
| CHEMBL159929 | — | — | 1 | 7.58 |
| CHEMBL143022 | — | — | 1 | 7.28 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL164471 | — | Ki | = | 0.5623 | nM | 9.25 |
| CHEMBL143027 | — | Ki | = | 11.22 | nM | 7.95 |
| CHEMBL159929 | — | Ki | = | 26.3 | nM | 7.58 |
| CHEMBL143022 | — | Ki | = | 52.48 | nM | 7.28 |