Assay Detail
Binding
CHEMBL1027136
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of methionine aminopeptidase 1
6
Total Activities
6
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Confidence | 8 — Homologous single protein target |
| Curated By | Intermediate |
Publication
A selective account of effective paradigms and significant outcomes in the discovery of inspirational marine natural products.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 6 | 5.64 | 5.70 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL327579 | — | — | 1 | 5.70 |
| CHEMBL256279 | BENGAMIDE A | — | 1 | 5.70 |
| CHEMBL539894 | BENGAMIDE O | — | 1 | 5.52 |
| CHEMBL424278 | O-CHLOROACETYLCARBAMOYLFUMAGILLOL | 2.0 | 1 | - |
| CHEMBL32838 | FUMAGILLIN | 2.0 | 1 | - |
| CHEMBL562231 | OVALICIN | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL327579 | — | IC50 | = | 2000.0 | nM | 5.70 |
| CHEMBL256279 | BENGAMIDE A | IC50 | = | 2000.0 | nM | 5.70 |
| CHEMBL539894 | BENGAMIDE O | IC50 | = | 3000.0 | nM | 5.52 |
| CHEMBL424278 | O-CHLOROACETYLCARBAMOYLFUMAGILLOL | IC50 | - | — | - | |
| CHEMBL32838 | FUMAGILLIN | IC50 | - | — | - | |
| CHEMBL562231 | OVALICIN | IC50 | - | — | - |