Assay Detail
Binding
CHEMBL1027377
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Inhibition of human telomerase assessed as unincorporated [alpha32P]dGTP
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
BRACO19 analog dimers with improved inhibition of telomerase and hPot 1.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 4 | 5.21 | 5.40 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL448813 | — | — | 1 | 5.40 |
| CHEMBL336434 | — | — | 1 | 5.27 |
| CHEMBL443702 | — | — | 1 | 5.12 |
| CHEMBL506865 | — | — | 1 | 5.05 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL448813 | — | IC50 | = | 4000.0 | nM | 5.40 |
| CHEMBL336434 | — | IC50 | = | 5400.0 | nM | 5.27 |
| CHEMBL443702 | — | IC50 | = | 7500.0 | nM | 5.12 |
| CHEMBL506865 | — | IC50 | = | 9000.0 | nM | 5.05 |