Assay Detail
Functional
CHEMBL1028241
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Cytotoxicity against human MCF7 cells by MTT assay
6
Total Activities
6
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | MCF7 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Lignans from the roots of Saururus chinensis.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 6 | 4.44 | 5.00 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL65 | CAMPTOTHECIN | -1.0 | 1 | 5.00 |
| CHEMBL491245 | SAUCERNEOL G | — | 1 | 4.19 |
| CHEMBL483449 | SAUCERNEOL H | — | 1 | 4.14 |
| CHEMBL519080 | SAUCERNEOL F | — | 1 | - |
| CHEMBL520077 | SAUCERNEOL D | — | 1 | - |
| CHEMBL483652 | SAUCERNEOL I | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL65 | CAMPTOTHECIN | IC50 | = | 10000.0 | nM | 5.00 |
| CHEMBL491245 | SAUCERNEOL G | IC50 | = | 64000.0 | nM | 4.19 |
| CHEMBL483449 | SAUCERNEOL H | IC50 | = | 72000.0 | nM | 4.14 |
| CHEMBL519080 | SAUCERNEOL F | IC50 | > | 100000.0 | nM | - |
| CHEMBL520077 | SAUCERNEOL D | IC50 | > | 100000.0 | nM | - |
| CHEMBL483652 | SAUCERNEOL I | IC50 | > | 100000.0 | nM | - |