Assay Detail

CHEMBL1029065

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Functional

Cytotoxicity against human HeLa cells

ChEMBL ↗

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Target

HeLa (CHEMBL399) ↗

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Primary target HeLa

CHEMBL399

Anchored from Assay target.

Protein identity HeLa

Disease frame Disease evidence pending

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Review focus Open DB context pending

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Total Activities

Compounds Tested

Activity Types

Assay Parameters

Assay Information

Assay Type	Functional
Organism	Homo sapiens
Cell Type	HeLa
Confidence	1 — Organism
Curated By	Autocuration

Target

HeLa (CHEMBL399) ↗

Type	CELL-LINE
Organism	Homo sapiens

Publication

A novel sesquiterpene quinone from Hainan sponge Dysidea villosa.

Li Y, Zhang Y, Shen X, Guo YW.
Bioorg Med Chem Lett (2009) 19 : 390 -392
PubMed 19091557 · DOI

Activity Statistics

Type	Count	Avg pChEMBL	Best pChEMBL
IC50	2	4.99	5.26

Compounds Tested

Compound	Name	Phase	Activities	Best pChEMBL
CHEMBL477692	BOLINAQUINONE	—	1	5.26
CHEMBL460643	—	—	1	4.71

Activity Data

Compound	Name	Type	Rel.	Value	Units	pChEMBL
CHEMBL477692	BOLINAQUINONE	IC50	=	5450.0	nM	5.26
CHEMBL460643	—	IC50	=	19450.0	nM	4.71