Assay Detail
Binding
CHEMBL1029214
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of electric eel AChE by Ellman's method
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Electrophorus electricus |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Structure and anti-acetylcholinesterase activity of 4 alpha-(hydroxymethyl)-4 alpha-demethylterritrem B.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 4 | 7.51 | 9.37 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL464537 | 4ALPHA-(HYDROXYMETHYL)-4ALPHA-DEMETHYLTERRITREM B | — | 1 | 9.37 |
| CHEMBL464538 | — | — | 1 | 8.00 |
| CHEMBL24686 | TERRITREM B | — | 1 | 6.58 |
| CHEMBL465764 | — | — | 1 | 6.10 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL464537 | 4ALPHA-(HYDROXYMETHYL)-4ALPHA-DEMETHYLTERRITREM B | IC50 | = | 0.423 | nM | 9.37 |
| CHEMBL464538 | — | IC50 | = | 10.0 | nM | 8.00 |
| CHEMBL24686 | TERRITREM B | IC50 | = | 260.0 | nM | 6.58 |
| CHEMBL465764 | — | IC50 | = | 790.0 | nM | 6.10 |