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Assay Detail

CHEMBL1032137

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Antimalarial activity after 48 hrs against Plasmodium falciparum T9-96 by [3H]hypoxanthine uptake
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Plasmodium falciparum
Confidence 1 — Organism
Curated By Autocuration

Target

Plasmodium falciparum (CHEMBL364)
Type ORGANISM
Organism Plasmodium falciparum

Publication

Design, synthesis and structure-activity relationships of (1H-pyridin-4-ylidene)amines as potential antimalarials.
Rodrigues T, Guedes RC, dos Santos DJ, Carrasco M, Gut J, Rosenthal PJ, Moreira R, Lopes F.
Bioorg Med Chem Lett (2009) 19 : 3476 -3480
PubMed 19467600 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 7.52 7.52

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL467584 1 7.52

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL467584 IC50 = 30.0 nM 7.52