Assay Detail
Binding
CHEMBL1032435
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Binding affinity to Mycobacterium tuberculosis APS reductase
10
Total Activities
10
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Mycobacterium tuberculosis |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
Structure-based virtual screening and biological evaluation of Mycobacterium tuberculosis adenosine 5'-phosphosulfate reductase inhibitors.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Kd | 10 | 4.58 | 5.17 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL433282 | — | — | 1 | 5.17 |
| CHEMBL515505 | — | — | 1 | 4.82 |
| CHEMBL505670 | — | — | 1 | 4.71 |
| CHEMBL508088 | — | — | 1 | 4.50 |
| CHEMBL512908 | — | — | 1 | 4.43 |
| CHEMBL447498 | — | — | 1 | 4.35 |
| CHEMBL1162522 | — | — | 1 | 4.33 |
| CHEMBL445269 | — | — | 1 | 4.32 |
| CHEMBL1162521 | — | — | 1 | - |
| CHEMBL1162523 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL433282 | — | Kd | = | 6810.0 | nM | 5.17 |
| CHEMBL515505 | — | Kd | = | 15190.0 | nM | 4.82 |
| CHEMBL505670 | — | Kd | = | 19510.0 | nM | 4.71 |
| CHEMBL508088 | — | Kd | = | 31790.0 | nM | 4.50 |
| CHEMBL512908 | — | Kd | = | 37110.0 | nM | 4.43 |
| CHEMBL447498 | — | Kd | = | 44590.0 | nM | 4.35 |
| CHEMBL1162522 | — | Kd | = | 46850.0 | nM | 4.33 |
| CHEMBL445269 | — | Kd | = | 48110.0 | nM | 4.32 |
| CHEMBL1162521 | — | Kd | = | 180350.0 | nM | - |
| CHEMBL1162523 | — | Kd | = | 127190.0 | nM | - |