Assay Detail
Binding
CHEMBL1033061
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Displacement of [3H]ketanserin from 5HT2A receptor
5
Total Activities
5
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Confidence | 8 — Homologous single protein target |
| Curated By | Intermediate |
Publication
Structure-activity relationships for a novel series of dopamine D2-like receptor ligands based on N-substituted 3-aryl-8-azabicyclo[3.2.1]octan-3-ol.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 5 | 6.19 | 7.15 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL3084512 | — | — | 1 | 7.15 |
| CHEMBL3084515 | — | — | 1 | 6.77 |
| CHEMBL445102 | — | — | 1 | 6.16 |
| CHEMBL3084503 | — | — | 1 | 5.55 |
| CHEMBL3084502 | — | — | 1 | 5.32 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL3084512 | — | Ki | = | 70.1 | nM | 7.15 |
| CHEMBL3084515 | — | Ki | = | 171.0 | nM | 6.77 |
| CHEMBL445102 | — | Ki | = | 695.0 | nM | 6.16 |
| CHEMBL3084503 | — | Ki | = | 2800.0 | nM | 5.55 |
| CHEMBL3084502 | — | Ki | = | 4770.0 | nM | 5.32 |