Assay Detail
Binding
CHEMBL1033064
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Displacement of [125I]IABN from human dopamine D4 receptor
5
Total Activities
5
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Confidence | 8 — Homologous single protein target |
| Curated By | Intermediate |
Publication
Structure-activity relationships for a novel series of dopamine D2-like receptor ligands based on N-substituted 3-aryl-8-azabicyclo[3.2.1]octan-3-ol.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 5 | 6.49 | 6.85 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL3084512 | — | — | 1 | 6.85 |
| CHEMBL3084515 | — | — | 1 | 6.71 |
| CHEMBL3084503 | — | — | 1 | 6.44 |
| CHEMBL445102 | — | — | 1 | 5.96 |
| CHEMBL3084502 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL3084512 | — | Ki | = | 140.0 | nM | 6.85 |
| CHEMBL3084515 | — | Ki | = | 195.0 | nM | 6.71 |
| CHEMBL3084503 | — | Ki | = | 364.0 | nM | 6.44 |
| CHEMBL445102 | — | Ki | = | 1100.0 | nM | 5.96 |
| CHEMBL3084502 | — | Ki | > | 5000.0 | nM | - |