Assay Detail
Binding
CHEMBL1033293
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of HIV1 integrase 3' processing activity
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Human immunodeficiency virus 1 |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Target
Human immunodeficiency virus type 1 integrase (CHEMBL3471) ↗| Type | SINGLE PROTEIN |
| Organism | Human immunodeficiency virus 1 |
Publication
Natural product-based anti-HIV drug discovery and development facilitated by the NCI developmental therapeutics program.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 1 | 5.31 | 5.31 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL366861 | FUMARPROTOCETRARIC ACID | — | 1 | 5.31 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL366861 | FUMARPROTOCETRARIC ACID | IC50 | = | 4900.0 | nM | 5.31 |