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Assay Detail

CHEMBL1034004

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Functional
Antiviral activity against Human rhinovirus
22
Total Activities
22
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Human rhinovirus sp.
Confidence 1 — Organism
Curated By Autocuration

Target

Human rhinovirus sp. (CHEMBL612470)
Type ORGANISM
Organism Human rhinovirus sp.

Publication

Unified QSAR approach to antimicrobials. 4. Multi-target QSAR modeling and comparative multi-distance study of the giant components of antiviral drug-drug complex networks.
Prado-Prado FJ, Martinez de la Vega O, Uriarte E, Ubeira FM, Chou KC, González-Díaz H.
Bioorg Med Chem (2009) 17 : 569 -575
PubMed 19112024 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 22 6.74 8.52

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL297598 1 8.52
CHEMBL43972 1 8.52
CHEMBL108922 1 7.85
CHEMBL44129 1 7.85
CHEMBL44567 1 7.80
CHEMBL107873 1 7.58
CHEMBL43385 1 6.98
CHEMBL62681 1 6.82
CHEMBL293441 1 6.80
CHEMBL40872 1 6.75
CHEMBL302419 1 6.75
CHEMBL44284 1 6.62
CHEMBL44022 1 6.33
CHEMBL42513 1 6.29
CHEMBL295096 1 6.05
CHEMBL292942 1 5.92
CHEMBL61646 1 5.89
CHEMBL61443 1 5.85
CHEMBL479531 1 5.74
CHEMBL294332 1 5.71
CHEMBL290485 1 5.00
CHEMBL243876 1 -

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL297598 IC50 = 3.0 nM 8.52
CHEMBL43972 IC50 = 3.0 nM 8.52
CHEMBL108922 IC50 = 14.0 nM 7.85
CHEMBL44129 IC50 = 14.0 nM 7.85
CHEMBL44567 IC50 = 16.0 nM 7.80
CHEMBL107873 IC50 = 26.0 nM 7.58
CHEMBL43385 IC50 = 104.0 nM 6.98
CHEMBL62681 IC50 = 150.0 nM 6.82
CHEMBL293441 IC50 = 160.0 nM 6.80
CHEMBL40872 IC50 = 178.0 nM 6.75
CHEMBL302419 IC50 = 180.0 nM 6.75
CHEMBL44284 IC50 = 240.0 nM 6.62
CHEMBL44022 IC50 = 469.0 nM 6.33
CHEMBL42513 IC50 = 518.0 nM 6.29
CHEMBL295096 IC50 = 888.0 nM 6.05
CHEMBL292942 IC50 = 1190.0 nM 5.92
CHEMBL61646 IC50 = 1290.0 nM 5.89
CHEMBL61443 IC50 = 1400.0 nM 5.85
CHEMBL479531 IC50 = 1810.0 nM 5.74
CHEMBL294332 IC50 = 1940.0 nM 5.71
CHEMBL290485 IC50 = 10000.0 nM 5.00
CHEMBL243876 IC50 = 200000.0 nM -