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Assay Detail

CHEMBL1034039

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Displacement of [125I]DOI from human 5HT2A receptor by liquid scintillation counting
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Homo sapiens
Confidence 9 — Direct single protein target
Curated By Autocuration

Target

5-hydroxytryptamine receptor 2A (CHEMBL224)
Type SINGLE PROTEIN
Organism Homo sapiens

Publication

Synthesis and evaluation of ligands for D2-like receptors: the role of common pharmacophoric groups.
Sikazwe DM, Nkansah NT, Altundas R, Zhu XY, Roth BL, Setola V, Ablordeppey SY.
Bioorg Med Chem (2009) 17 : 1716 -1723
PubMed 19155177 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
Ki 1 6.71 6.71

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL476109 1 6.71

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL476109 Ki = 194.8 nM 6.71