Assay Detail
Functional
CHEMBL1034069
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Cytotoxicity against human SupT1 cells after 24 hrs by CellTiter-Blue assay
7
Total Activities
6
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | SUP-T1 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Ceramides: branched alkyl chains in the sphingolipid siblings of diacylglycerol improve biological potency.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 7 | 4.41 | 4.81 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL472237 | — | — | 1 | 4.81 |
| CHEMBL471621 | — | — | 1 | 4.54 |
| CHEMBL105867 | — | — | 2 | 4.38 |
| CHEMBL224877 | — | — | 1 | 4.32 |
| CHEMBL444967 | — | — | 1 | 4.28 |
| CHEMBL471622 | — | — | 1 | 4.12 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL472237 | — | IC50 | = | 15450.0 | nM | 4.81 |
| CHEMBL471621 | — | IC50 | = | 29080.0 | nM | 4.54 |
| CHEMBL105867 | — | IC50 | = | 41440.0 | nM | 4.38 |
| CHEMBL224877 | — | IC50 | = | 48010.0 | nM | 4.32 |
| CHEMBL444967 | — | IC50 | = | 52890.0 | nM | 4.28 |
| CHEMBL471622 | — | IC50 | = | 76300.0 | nM | 4.12 |
| CHEMBL105867 | — | IC50 | > | 200000.0 | nM | - |