Assay Detail
Functional
CHEMBL1034188
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Antileishmanial activity against Leishmania donovani LV9 promastigotes after 96 hrs by MTT assay
7
Total Activities
7
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Leishmania donovani |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Leishmanicidal and antiplasmodial activity of constituents of Smirnowia iranica.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 7 | 5.22 | 7.70 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL267345 | AMPHOTERICIN B | 4.0 | 1 | 7.70 |
| CHEMBL501755 | — | — | 1 | 5.16 |
| CHEMBL498724 | SMIRANICIN | — | 1 | 4.64 |
| CHEMBL498725 | GLYASPERIN H | — | 1 | 4.60 |
| CHEMBL454996 | — | — | 1 | 4.01 |
| CHEMBL501754 | — | — | 1 | - |
| CHEMBL489518 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL267345 | AMPHOTERICIN B | IC50 | = | 20.0 | nM | 7.70 |
| CHEMBL501755 | — | IC50 | = | 6900.0 | nM | 5.16 |
| CHEMBL498724 | SMIRANICIN | IC50 | = | 22900.0 | nM | 4.64 |
| CHEMBL498725 | GLYASPERIN H | IC50 | = | 25300.0 | nM | 4.60 |
| CHEMBL454996 | — | IC50 | = | 97000.0 | nM | 4.01 |
| CHEMBL501754 | — | IC50 | = | 232000.0 | nM | - |
| CHEMBL489518 | — | IC50 | = | 395000.0 | nM | - |