Assay Detail
Binding
CHEMBL1034394
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Inhibition of Penicillium decumbens alpha-L-rhamnosidase assessed as p-nitrophenol release after 30 mins by spectrophotometry
6
Total Activities
6
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Penicillium decumbens |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
New polyhydroxylated pyrrolidine, piperidine, and pyrrolizidine alkaloids from Scilla sibirica.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 6 | 4.60 | 5.75 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL179347 | — | — | 1 | 5.75 |
| CHEMBL407337 | — | — | 1 | 4.03 |
| CHEMBL503021 | — | — | 1 | 4.03 |
| CHEMBL307429 | DUVOGLUSTAT | 2.0 | 1 | - |
| CHEMBL522570 | — | — | 1 | - |
| CHEMBL519261 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL179347 | — | IC50 | = | 1800.0 | nM | 5.75 |
| CHEMBL407337 | — | IC50 | = | 94000.0 | nM | 4.03 |
| CHEMBL503021 | — | IC50 | = | 94000.0 | nM | 4.03 |
| CHEMBL307429 | DUVOGLUSTAT | IC50 | = | 850000.0 | nM | - |
| CHEMBL522570 | — | IC50 | - | — | - | |
| CHEMBL519261 | — | IC50 | - | — | - |