Skip to main content
Free research Free research Free assay review with research home and workspace preview
Quick search ChEMBL 36
Assay Detail

CHEMBL1034553

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Inhibition of HIF1 by luciferase reporter gene assay
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Confidence 0 — Uncurated / Unknown
Curated By Autocuration

Target

Unchecked (CHEMBL612545)
Type UNCHECKED

Publication

Analysis of HIF-1 inhibition by manassantin A and analogues with modified tetrahydrofuran configurations.
Kasper AC, Moon EJ, Hu X, Park Y, Wooten CM, Kim H, Yang W, Dewhirst MW, Hong J.
Bioorg Med Chem Lett (2009) 19 : 3783 -3786
PubMed 19423348 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 9.00 9.00

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL2021442 MANASSANTIN A 1 9.00

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL2021442 MANASSANTIN A IC50 = 1.0 nM 9.00