Assay Detail
Binding
CHEMBL1035606
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Binding affinity to vasopressin V1a receptor
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Confidence | 8 — Homologous single protein target |
| Curated By | Intermediate |
Publication
Discovery and optimization of highly ligand-efficient oxytocin receptor antagonists using structure-based drug design.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 2 | 7.90 | 8.33 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL382301 | ATOSIBAN | 4.0 | 1 | 8.33 |
| CHEMBL395429 | OXYTOCIN | 4.0 | 1 | 7.46 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL382301 | ATOSIBAN | Ki | = | 4.7 | nM | 8.33 |
| CHEMBL395429 | OXYTOCIN | Ki | = | 34.9 | nM | 7.46 |