Assay Detail
Functional
CHEMBL1035916
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Antiproliferative activity against human Caco-2 cells after 72 hrs by MTT assay
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | Caco-2 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Synthesis, mechanistic studies, and anti-proliferative activity of glutathione/glutathione S-transferase-activated nitric oxide prodrugs.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 5.79 | 6.00 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL212378 | — | — | 1 | 6.00 |
| CHEMBL455983 | — | — | 1 | 5.58 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL212378 | — | IC50 | = | 1000.0 | nM | 6.00 |
| CHEMBL455983 | — | IC50 | = | 2600.0 | nM | 5.58 |