Assay Detail
Functional
CHEMBL1036042
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Cytotoxicity against human RPMI8226/S cells after 72 hrs by trypan blue exclusion method
6
Total Activities
5
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | RPMI8226/S |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Cytotoxic cyclotides from Viola tricolor.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 6 | 6.02 | 7.00 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL525223 | CYCLOVIOLACIN O2 | — | 1 | 7.00 |
| CHEMBL53463 | DOXORUBICIN | 4.0 | 1 | 7.00 |
| CHEMBL526697 | VITRI A | — | 1 | 6.00 |
| CHEMBL526529 | — | — | 1 | 5.52 |
| CHEMBL501039 | — | — | 2 | 5.40 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL525223 | CYCLOVIOLACIN O2 | IC50 | = | 100.0 | nM | 7.00 |
| CHEMBL53463 | DOXORUBICIN | IC50 | = | 100.0 | nM | 7.00 |
| CHEMBL526697 | VITRI A | IC50 | = | 1000.0 | nM | 6.00 |
| CHEMBL526529 | — | IC50 | = | 3000.0 | nM | 5.52 |
| CHEMBL501039 | — | IC50 | = | 4000.0 | nM | 5.40 |
| CHEMBL501039 | — | IC50 | = | 6000.0 | nM | 5.22 |