Assay Detail
Binding
CHEMBL1036437
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of recombinant HDAC1 transfected in mouse NIH/3T3 assessed as [3H]acetic acid release by scintillation counting
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Cell Type | NIH3T3 |
| Confidence | 8 — Homologous single protein target |
| Curated By | Intermediate |
Publication
Design and synthesis of novel hybrid benzamide-peptide histone deacetylase inhibitors.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 1 | 9.96 | 9.96 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL2000089 | TRAPOXIN B | — | 1 | 9.96 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL2000089 | TRAPOXIN B | IC50 | = | 0.11 | nM | 9.96 |