Assay Detail
Binding
CHEMBL1037629
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Activity at PPARalpha
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Confidence | 8 — Homologous single protein target |
| Curated By | Intermediate |
Target
Peroxisome proliferator-activated receptor alpha (CHEMBL239) ↗| Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
Publication
Phenoxy herbicides and fibrates potently inhibit the human chemosensory receptor subunit T1R3.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 2 | 4.30 | 4.30 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL683 | CLOFIBRIC ACID | 2.0 | 1 | 4.30 |
| CHEMBL264374 | BEZAFIBRATE | 3.0 | 1 | 4.30 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL683 | CLOFIBRIC ACID | EC50 | = | 50000.0 | nM | 4.30 |
| CHEMBL264374 | BEZAFIBRATE | EC50 | = | 50000.0 | nM | 4.30 |