Assay Detail
Functional
CHEMBL1038646
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Cytotoxicity against human A549 cells by MTT assay
9
Total Activities
9
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | A549 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Phytochemical investigation of labdane diterpenes from the rhizomes of Hedychium spicatum and their cytotoxic activity.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 9 | 4.44 | 5.02 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL44657 | ETOPOSIDE | 4.0 | 1 | 5.02 |
| CHEMBL117 | CHRYSIN | — | 1 | 4.70 |
| CHEMBL582854 | — | — | 1 | 4.42 |
| CHEMBL318196 | ETHYL CINNAMATE | — | 1 | 4.30 |
| CHEMBL511204 | YUNNACORONARIN D | — | 1 | 4.29 |
| CHEMBL573722 | SPICATANOIC ACID | — | 1 | 4.28 |
| CHEMBL109252 | CORONARIN E | — | 1 | 4.27 |
| CHEMBL507971 | — | — | 1 | 4.21 |
| CHEMBL95956 | 4-METHOXY ETHYL CINNAMATE | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL44657 | ETOPOSIDE | IC50 | = | 9510.0 | nM | 5.02 |
| CHEMBL117 | CHRYSIN | IC50 | = | 19880.0 | nM | 4.70 |
| CHEMBL582854 | — | IC50 | = | 37850.0 | nM | 4.42 |
| CHEMBL318196 | ETHYL CINNAMATE | IC50 | = | 50350.0 | nM | 4.30 |
| CHEMBL511204 | YUNNACORONARIN D | IC50 | = | 51240.0 | nM | 4.29 |
| CHEMBL573722 | SPICATANOIC ACID | IC50 | = | 51970.0 | nM | 4.28 |
| CHEMBL109252 | CORONARIN E | IC50 | = | 53260.0 | nM | 4.27 |
| CHEMBL507971 | — | IC50 | = | 61290.0 | nM | 4.21 |
| CHEMBL95956 | 4-METHOXY ETHYL CINNAMATE | IC50 | - | — | - |