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Assay Detail

CHEMBL1038964

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Binding affinity to sigma receptor
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Confidence 0 — Uncurated / Unknown
Curated By Autocuration

Target

Unchecked (CHEMBL612545)
Type UNCHECKED

Publication

Synthesis and opioid activity of enantiomeric N-substituted 2,3,4,4a,5,6,7,7a-octahydro-1H-benzofuro[3,2-e]isoquinolines.
Hsin LW, Chang LT, Rothman RB, Dersch CM, Fishback JA, Matsumoto RR.
J Med Chem (2010) 53 : 1392 -1396
PubMed 20055417 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
Ki 1 7.68 7.68

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL104042 1 7.68

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL104042 Ki = 21.0 nM 7.68