Assay Detail
Binding
CHEMBL1039764
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Inhibition of Penicillium decumbens Alpha-L-rhamnosidase by para-nitrophenolate release assay
10
Total Activities
10
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Penicillium decumbens |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
The spirocyclopropyl moiety as a methyl surrogate in the structure of l-fucosidase and l-rhamnosidase inhibitors.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 10 | 5.84 | 7.52 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL596461 | — | — | 1 | 7.52 |
| CHEMBL593716 | — | — | 1 | 6.85 |
| CHEMBL593715 | — | — | 1 | 6.00 |
| CHEMBL608711 | — | — | 1 | 5.52 |
| CHEMBL596462 | — | — | 1 | 5.50 |
| CHEMBL593918 | — | — | 1 | 5.26 |
| CHEMBL593681 | — | — | 1 | 4.24 |
| CHEMBL596048 | — | — | 1 | - |
| CHEMBL314772 | DEOXYFUCONOJIRIMYCIN | — | 1 | - |
| CHEMBL593679 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL596461 | — | Ki | = | 30.0 | nM | 7.52 |
| CHEMBL593716 | — | Ki | = | 140.0 | nM | 6.85 |
| CHEMBL593715 | — | Ki | = | 1000.0 | nM | 6.00 |
| CHEMBL608711 | — | Ki | = | 3000.0 | nM | 5.52 |
| CHEMBL596462 | — | Ki | = | 3200.0 | nM | 5.50 |
| CHEMBL593918 | — | Ki | = | 5500.0 | nM | 5.26 |
| CHEMBL593681 | — | Ki | = | 57000.0 | nM | 4.24 |
| CHEMBL596048 | — | Ki | - | — | - | |
| CHEMBL314772 | DEOXYFUCONOJIRIMYCIN | Ki | - | — | - | |
| CHEMBL593679 | — | Ki | - | — | - |