Assay Detail
Binding
CHEMBL1040862
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Inhibition of human Cathepsin C
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Intermediate |
Publication
Identification and optimization of inhibitors of Trypanosomal cysteine proteases: cruzain, rhodesain, and TbCatB.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 6.28 | 7.46 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL567341 | — | — | 1 | 7.46 |
| CHEMBL567134 | — | — | 1 | 6.23 |
| CHEMBL578159 | — | — | 1 | 5.16 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL567341 | — | IC50 | = | 34.67 | nM | 7.46 |
| CHEMBL567134 | — | IC50 | = | 588.84 | nM | 6.23 |
| CHEMBL578159 | — | IC50 | = | 6918.31 | nM | 5.16 |