Assay Detail
Binding
CHEMBL1041609
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Inhibition of Spodoptera litura beta-N-acetylglucosaminidase by pNP-GlcNAc substrate hydrolysis assay
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Spodoptera litura |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
Pochonicine, a polyhydroxylated pyrrolizidine alkaloid from fungus Pochonia suchlasporia var. suchlasporia TAMA 87 as a potent beta-N-acetylglucosaminidase inhibitor.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 8.23 | 8.23 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL596543 | NAGSTATIN | — | 1 | 8.23 |
| CHEMBL593689 | POCHONICINE | — | 1 | 8.22 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL596543 | NAGSTATIN | IC50 | = | 5.85 | nM | 8.23 |
| CHEMBL593689 | POCHONICINE | IC50 | = | 5.96 | nM | 8.22 |