Assay Detail
Binding
CHEMBL1042552
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Inhibition of mouse recombinant serine racemase transfected in bacterial expression system
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Mus musculus |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Hydroxamic acids as a novel family of serine racemase inhibitors: mechanistic analysis reveals different modes of interaction with the pyridoxal-5'-phosphate cofactor.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 3 | 4.26 | 4.37 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL568192 | — | — | 1 | 4.37 |
| CHEMBL7942 | MALONIC ACID | — | 1 | 4.15 |
| CHEMBL216796 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL568192 | — | Ki | = | 43000.0 | nM | 4.37 |
| CHEMBL7942 | MALONIC ACID | Ki | = | 71000.0 | nM | 4.15 |
| CHEMBL216796 | — | Ki | = | 1640000.0 | nM | - |