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Assay Detail

CHEMBL1042583

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Binding affinity to reindeer beta-lactoglobulin by fluorescence spectroscopy
4
Total Activities
4
Compounds Tested
2
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Rangifer tarandus
Confidence 0 — Uncurated / Unknown
Curated By Autocuration

Target

Unchecked (CHEMBL612545)
Type UNCHECKED

Publication

The binding of synthetic retinoids to lipocalin beta-lactoglobulins.
Riihimäki-Lampén LH, Vainio MJ, Vahermo M, Pohjala LL, Heikura JM, Valkonen KH, Virtanen VT, Yli-Kauhaluoma JT, Vuorela PM.
J Med Chem (2010) 53 : 514 -518
PubMed 19938842 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
Kd 2 6.84 6.97
Activity 2 - -

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL571411 1 6.97
CHEMBL986 RETINOL 4.0 1 6.70
CHEMBL275311 1 -
CHEMBL7301 FENRETINIDE 3.0 1 -

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL571411 Kd = 107.0 nM 6.97
CHEMBL986 RETINOL Kd = 200.0 nM 6.70
CHEMBL275311 Activity - -
CHEMBL7301 FENRETINIDE Activity - -