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Assay Detail

CHEMBL1045111

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Antioxidant activity assessed as DPPH radical scavenging activity after 30 mins by spectrophotometry
24
Total Activities
13
Compounds Tested
2
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Confidence 3 — Cell-line / Tissue
Curated By Autocuration

Publication

Antioxidant efficacy of iridoid and phenylethanoid glycosides from the medicinal plant Teucrium chamaedris in cell-free systems.
Pacifico S, D'Abrosca B, Pascarella MT, Letizia M, Uzzo P, Piscopo V, Fiorentino A.
Bioorg Med Chem (2009) 17 : 6173 -6179
PubMed 19674906 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 13 4.75 4.96
Activity 11 - -

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL595383 2 4.96
CHEMBL608705 2 4.85
CHEMBL444478 ACETOSIDE 2.0 2 4.82
CHEMBL595544 2 4.78
CHEMBL153 TROLOX 1 4.68
CHEMBL595333 2 4.42
CHEMBL606147 1 -
CHEMBL593634 2 -
CHEMBL595773 2 -
CHEMBL596187 2 -
CHEMBL605532 2 -
CHEMBL595293 2 -
CHEMBL595516 2 -

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL595383 IC50 = 11000.0 nM 4.96
CHEMBL608705 IC50 = 14000.0 nM 4.85
CHEMBL444478 ACETOSIDE IC50 = 15300.0 nM 4.82
CHEMBL595544 IC50 = 16500.0 nM 4.78
CHEMBL153 TROLOX IC50 = 21000.0 nM 4.68
CHEMBL595333 IC50 = 38300.0 nM 4.42
CHEMBL606147 IC50 > 300000.0 nM -
CHEMBL593634 IC50 > 300000.0 nM -
CHEMBL595773 IC50 > 300000.0 nM -
CHEMBL596187 IC50 > 300000.0 nM -
CHEMBL605532 IC50 > 300000.0 nM -
CHEMBL595293 IC50 > 300000.0 nM -
CHEMBL595516 IC50 > 300000.0 nM -
CHEMBL593634 Activity - -
CHEMBL595773 Activity - -
CHEMBL596187 Activity - -
CHEMBL605532 Activity - -
CHEMBL595293 Activity - -
CHEMBL595516 Activity - -
CHEMBL444478 ACETOSIDE Activity - -
CHEMBL595544 Activity - -
CHEMBL595333 Activity - -
CHEMBL608705 Activity - -
CHEMBL595383 Activity - -