Assay Detail
Binding
CHEMBL1045262
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Binding affinity to Bacillus anthracis DHPS expressed in Escherichia coli BL21 (DE3) after 30 mins by isothermal titration calorimetry
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Bacillus anthracis |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Structural studies of pterin-based inhibitors of dihydropteroate synthase.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Kd | 2 | 5.27 | 5.28 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL577547 | — | — | 1 | 5.28 |
| CHEMBL542 | AMINOBENZOIC ACID | -1.0 | 1 | 5.25 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL577547 | — | Kd | = | 5260.0 | nM | 5.28 |
| CHEMBL542 | AMINOBENZOIC ACID | Kd | = | 5620.0 | nM | 5.25 |