Assay Detail
Functional
CHEMBL1045385
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Antiviral activity against HSV1 KOS infected in HEL cells assessed as inhibition of virus-induced cytopathicity
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Human alphaherpesvirus 1 |
| Cell Type | HEL |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Application of the dipeptidyl peptidase IV (DPPIV/CD26) based prodrug approach to different amine-containing drugs.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 2 | 4.37 | 4.46 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL1090 | VIDARABINE | 4.0 | 1 | 4.46 |
| CHEMBL572009 | — | — | 1 | 4.27 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL1090 | VIDARABINE | EC50 | = | 35000.0 | nM | 4.46 |
| CHEMBL572009 | — | EC50 | = | 54000.0 | nM | 4.27 |