Assay Detail
Binding
CHEMBL1045467
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of recombinant CK1epsilon by Cherenkov counting in presence of 20 uM ATP
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Confidence | 8 — Homologous single protein target |
| Curated By | Intermediate |
Publication
3,4-Diaryl-isoxazoles and -imidazoles as potent dual inhibitors of p38alpha mitogen activated protein kinase and casein kinase 1delta.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 6.75 | 7.14 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL569114 | — | — | 1 | 7.14 |
| CHEMBL572006 | — | — | 1 | 6.35 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL569114 | — | IC50 | = | 73.0 | nM | 7.14 |
| CHEMBL572006 | — | IC50 | = | 447.0 | nM | 6.35 |