Assay Detail
Functional
CHEMBL1045656
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Antiproliferative activity against human SK-N-MC cells by MTT assay
5
Total Activities
5
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | SK-N-MC |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Thiosemicarbazones from the old to new: iron chelators that are more than just ribonucleotide reductase inhibitors.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 5 | 6.00 | 6.00 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL255068 | — | — | 1 | 6.00 |
| CHEMBL254856 | — | — | 1 | 6.00 |
| CHEMBL3217285 | — | — | 1 | 6.00 |
| CHEMBL254027 | — | — | 1 | - |
| CHEMBL399686 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL255068 | — | IC50 | = | 1000.0 | nM | 6.00 |
| CHEMBL254856 | — | IC50 | = | 1000.0 | nM | 6.00 |
| CHEMBL3217285 | — | IC50 | = | 1000.0 | nM | 6.00 |
| CHEMBL254027 | — | IC50 | > | 23000.0 | nM | - |
| CHEMBL399686 | — | IC50 | > | 23000.0 | nM | - |